Today techs Belite Bio Publicizes Late-Breaking Presentation on the

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  • 1-year interim information from the 2-year Section 1b/2 trial of LBS-008 in adolescent STGD1 to be offered

SAN DIEGO, Sept. 23, 2022 (GLOBE NEWSWIRE) — Belite BioInc (NASDAQ: BLTE), a San Diego based mostly scientific stage biopharmaceutical drug improvement firm concentrating on at the moment untreatable eye ailments, as we speak introduced that the 1-year interim information from the 2-year Section 1b/2 trial of LBS-008 in adolescent STGD1 can be offered on the “Late Breaking Growth” session on the American Academy of Ophthalmology Annual Assembly (AAO 2022) being held September 30 – October 3, 2022 in Chicago.

Particulars of the presentation are as follows:

Title: A 2-year Section 1b/2 Research of the Security and Tolerability of Tinlarebant in Adolescent STGD1 Topics: Interim Findings
Summary Quantity: 30071744
Part: Part X, Late Breaking Developments, Half II
Date and Time: Saturday, Oct 1, 2022 – 9:20 AM – 9:25 AM (Central Daylight Time)
Location: McCormick Place – Arie Crown, Chicago
Presenting Creator: John Grigg, MBBS

For extra details about the AAO 2022 annual assembly please go to: https://www.aao.org/annual-meeting.

About LBS-008

LBS-008 is a novel oral remedy supposed as an early intervention to forestall the buildup of poisons within the eye that trigger STGD1 and contribute to Dry AMD. These toxins are by-products of vitamin A within the visible cycle, which relies on the availability of vitamin A (retinol) to the attention. LBS-008 works by lowering and sustaining ranges of serum retinol binding protein 4 (RBP4), the only real service protein for transport of retinol into the attention. By modulating today techs the quantity of retinol getting into the attention, LBS-008 reduces the formation of vitamin A-based toxins which have been implicated in STGD1 and Dry AMD with the intention to preserve the well being of retinal tissues. LBS-008 has been granted Quick today techs Observe Designation, Uncommon Pediatric Illness Designation within the U.S., and Orphan Drug Designation within the U.S. and Europe for the therapy of STGD1.

Stargardt Illness

STGD1 is the commonest inherited retinal dystrophy (inflicting blurring or lack of central imaginative and prescient) in each adults and kids. The illness is attributable to a dysfunctional retina-specific gene (ABCA4) which ends up in large accumulation of poisonous vitamin A byproducts (generally known as ‘bisretinoids’) within the retina resulting in retinal cell loss of life and progressive lack of central imaginative and prescient. The fluorescent properties of bisretinoids and the event of retinal imaging have helped ophthalmologists establish and monitor illness development. STGD1 and Dry AMD share an analogous pathophysiology characterised by extreme accumulation of cytotoxic bisretinoids, retinal cell loss of life, and lack of imaginative and prescient. Imaginative and prescient loss happens slowly, regardless of peripheral growth of ‘lifeless retina’, till the illness reaches the middle of the attention (the macula).

About Belite Bio

Belite Bio is a San Diego based mostly scientific stage biopharmaceutical drug improvement firm concentrating on at the moment untreatable eye ailments, akin to atrophic age-related macular degeneration (generally generally known as superior Dry AMD) and Stargardt illness, and metabolic ailments. For extra info, observe us on Twitter, Instagram, LinkedIn, Fb or go to us at www.belitebio.com.

Vital Cautions Relating to Ahead Wanting Statements
This press launch comprises forward-looking statements, together with statements concerning the potential implications of scientific information for sufferers, and Belite Bio’s development of, and anticipated preclinical actions, scientific improvement, regulatory milestones, and commercialization of its product candidates. Precise outcomes could differ materially from these indicated within the forward-looking statements on account of numerous vital elements, together with however not restricted to Belite Bio’s potential to exhibit the security and efficacy of its drug candidates; the scientific outcomes for its drug candidates, which can not assist additional improvement or regulatory approval; the content material and timing of selections made by the related regulatory authorities concerning regulatory approval today techs of Belite Bio’s drug candidates; the potential efficacy of LBS-008 on the therapy of Dry AMD, in addition to these dangers extra absolutely mentioned within the “Threat Components” part in Belite Bio’s filings with the U.S. Securities and Trade Fee. All forward-looking statements are based mostly on info at the moment obtainable to Belite Bio, and Belite Bio undertakes no obligation to publicly replace or revise any forward-looking statements, whether or today techs not on account of new info, future occasions or in any other case, besides as could also be required by regulation.

Media and Investor Relations Contact:
Jennifer Wu /ir@belitebio.com
Tim McCarthy /tim@lifesciadvisors.com

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