Today techs Vital Milestone Reached for Evaxion Biotech’s EVX-01

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COPENHAGEN, Denmark, Sept. 21, 2022 (GLOBE NEWSWIRE) — Evaxion Biotech A/S (NASDAQ: EVAX) (“Evaxion” or the “Firm”), a clinical-stage biotechnology firm specializing within the improvement of AI-driven immunotherapies, reached an essential milestone asserting right now that it had enrolled its first affected person within the world section 2b medical trial of EVX-01, the Firm’s customized most cancers remedy for the remedy of melanoma.

Within the firm’s first section 2b medical trial, today techs Evaxion is evaluating the efficacy and security of EVX-01 in adults with metastatic melanoma. The trial is being carried out globally at medical websites throughout the US, Europe, and Australia in collaboration with Merck & Co., Inc., which is supplying the trial with its PD-1 inhibitor, KEYTRUDA®.

Sufferers enrolled within the section 2b medical trial will obtain normal of care remedy together with KEYTRUDA® together with EVX-01. Evaxion is chargeable for the conduct of the trial and Merck will provide the required KEYTRUDA®. Evaxion and Merck will proceed to collaborate as the info mature.

Erik Heegaard, Evaxion’s Chief Medical Officer, mentioned:

“We’re extraordinarily proud to take EVX-01 into the following medical improvement section, enrolling our first affected person within the clinic. We consider that this can assist to assist our efforts in growing new and extra efficacious therapies for sufferers affected by malignant melanoma. With this section 2b trial, we’re addressing a significant unmet medical want in a sign that has turn into a multi-billion-dollar market. Along with our collaborators at Merck, we hope to additional validate the promising knowledge generated in our section 1/2a examine, which we consider could probably pave the way in which for a lot wanted enchancment within the remedy panorama for melanoma and probably different cancers.”


  • EVX-01 is a novel customized most cancers immunotherapy primarily based on Evaxion’s proprietary PIONEER™ AI expertise, for the remedy of sufferers with melanoma.
  • Knowledge from the Section 1/2a medical trial of EVX-01 has proven that 67% of 9 sufferers benefitted from EVX-01 together with a PD-1 inhibitor (KEYTRUDA®) for the remedy of metastatic melanoma, in comparison with the historic knowledge of solely 40% benefiting from a PD-1 inhibitor alone
  • 22% of the sufferers within the Section 1/2a medical trial achieved an entire response (full restoration) with EVX-01 together with a PD-1 inhibitor (KEYTRUDA®).
  • The primary affected person within the Section 2b medical trial has now been enrolled
  • The Firm anticipates interim topline knowledge readout in H2 of 2023
  • For additional info, please check with KEYNOTE – D36 NCT05309421

KEYTRUDA® is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA.

About Evaxion
Evaxion Biotech A/S is a clinical-stage biotech firm growing AI-powered immunotherapies. With our proprietary and scalable AI expertise, we decode the human immune system to find and develop novel immunotherapies for most cancers, bacterial ailments, and viral infections. Evaxion has a broad pipeline of novel product candidates, together with three customized most cancers immunotherapies. It’s situated in Hørsholm, Denmark, and at present has 70 staff.

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